Comparison

DSAP Actinic Keratosis
**DSAP is easily identifiable by a slightly raised border ring (a fraction of a millimeter thick) around the lesion. The skin within the ring is somewhat thinned and mildly reddened or slightly brown, but a pale ring may or may not be seen just within the ridge. DSAP can spread out to a diameter of 10 mm or more. "Scaly", with no raised borders.
On average develop at about age 40 Develop typically after age 50
Mainly found on the lower arms and legs and arising more frequently on the lower legs of women than men. Only about 15% of patients have DSAP on the face. Although less common, the belly and back can be effected. Develop on the face, neck, ears, lips, arms and trunk
DSAP cells grow abnormally fast but not as fast as AK, and therefore not quite fast enough to properly absorb Efudex.  Typically DSAP only gets irritated and red from Efudex. AK cells grow abnormally fast and thus they absorb the Efudex medication (as the medication was designed to work).  Efudex causes a harsh skin eruption as AK cells are killed.
Although DSAP is labeled as "precancerous", development of DSAP into cancer is "uncommon".  Some of the redder spots can develop into cancer within 6 months.

** To really see the characteristic DSAP borders the skin should be dry, oil free, and viewed against a backdrop of lightThe "thread-like" borders are hard to detect and easily missed when skin is wet from vitamin E, sun screen, etc.